phosphoenolpyruvate is produced as an intermediate of glycolysis; phosphoenolpyruvate donates its high-energy phosphate group to enzyme I (EI); EI donates the phosphate group to a histidine-rich protein (HPr); HPr donates the phosphate group to enzyme IIA (EIIA); EIIA passes its phosphate group to Enzyme IIB (EIIB); as it enters the cell, glucose is phosphorylated by EIIB; glucose is transported across the membrane by enzyme IIC (EIIC); and the end product glucose-6-phosphate is now chemically different from the parent solute.
